Mechanisms of Exocytosis in Insulin-Secreting B-Cells and Glucagon-Secreting A-Cells
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چکیده
منابع مشابه
Mechanisms of exocytosis in insulin-secreting B-cells and glucagon-secreting A-cells.
In pancreatic B- and A-cells, metabolic stimuli regulate biochemical and electrical processes that culminate in Ca2+-influx and release of insulin or glucagon, respectively. Like in other (neuro)endocrine cells, Ca2+-influx triggers the rapid exocytosis of hormone-containing secretory granules. Only a small fraction of granules (<1% in insulin-secreting B-cells) can be released immediately, whi...
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ژورنال
عنوان ژورنال: Pharmacology & Toxicology
سال: 2003
ISSN: 0901-9928
DOI: 10.1034/j.1600-0773.2003.920102.x